MEG detects abnormal hippocampal activity in amyloid‐positive MCI
نویسندگان
چکیده
منابع مشابه
Normal and abnormal MEG activity in border zones of brain
Background. Brain lesions may influence their border zones by moving, compressing, infiltration, edema or by a mixture of all the above. Sources of evoked and spontaneous activity in border zones can be localized by the MEG. Methods. The inherent multisource problem can be handled by using spatial average techniques (Dipole-Density-Plot (DDP) and Current-Density-Plot (CDP)). The reliability was...
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Objectives. Aging is the major risk factor for Alzheimer Disease (AD) and Mild Cognitive Impairment (MCI). The aim of this study was to identify novel modifications of brain functional connectivity in MCI patients. MCI individuals were compared to healthy elderly subjects. Methods. We enrolled 37 subjects (age range 60-80 y.o.). Of these, 13 subjects were affected by MCI and 24 were age-matched...
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OBJECTIVE Shortly after infection, HIV enters the brain and causes widespread inflammation and neuronal damage, which ultimately leads to neuropsychological impairments. Despite a large body of neuroscience and imaging studies, the pathophysiology of these HIV-associated neurocognitive disorders (HAND) remains unresolved. Previous neuroimaging studies have shown greater activation in HIV-infect...
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Pathology in Alzheimer's disease (AD) starts in the entorhinal cortex and hippocampus. Because of their deep location, activity from these areas is difficult to record with conventional electro- or magnetoencephalography (EEG/MEG). The purpose of this study was to explore hippocampal activity in AD patients and healthy controls using "virtual MEG electrodes". We used resting-state MEG recording...
متن کاملAbnormal hippocampal axon bundling in EphB receptor mutant mice.
Axons travel frequently in bundles to reach their target. After arriving at the target, axon terminals defasciculate, migrate to topographically defined positions, and form synapses with appropriate target neurons. Here we present evidence that the B-type receptors of the erythropoietin-producing hepatocellular (Eph) family and a ligand, ephrin-B3, influence hippocampal axon defasciculation. Th...
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ژورنال
عنوان ژورنال: Alzheimer's & Dementia
سال: 2020
ISSN: 1552-5260,1552-5279
DOI: 10.1002/alz.040796